The Best Cat Urine Cleaners and Odor Removers

When you have a pet, you inevitably need a good cleaner – preferably a cleaner that gets rid of stains and completely eliminates unwanted odors. Because whether you just adopted a new pet, are fostering a few cats, have an ill pet, or your furry friend is now a senior, there will come a time when you’ll be mopping up accidents or cleaning up after bathroom training. A urine cleaner and odor remover is an essential item for any pet owner to have.

We reviewed dozens of cat urine cleaners and odor removers to identify the best. We considered how effective the product is, what the formula is made of, the method of delivery, and price. We looked at sprays, concentrated solutions, foams, and even outdoor applications.

Best Cat Urine Cleaner and Odor Remover Overall
Rocco & Roxie Professional Strength Stain & Odor Eliminator
Eliminate stains and odors with a cleaner that uses enzymatic bacteria to fight the problem at its source.

We chose Rocco & Roxie Professional Strength Stain & Odor Eliminator as our top choice for cat urine cleaners and odor removers. This professional strength cleaner gets rid of stubborn stains and unwanted odors using enzymatic methods. Enzymes fight stains where they originated, and don’t just cover up the problem.

The 5 Top-Rated Cat Urine Cleaners and Odor Removers

Editor's PicksBrandRating
Best OverallRocco & Roxie Professional Strength Stain & Odor Eliminator4.3
Best Cat Urine Carpet CleanerNature's Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo4.4
Best Budget BuyOUT! Advanced Stain and Odor Remover4.4
Best Cat Pee Enzyme CleanerSunny & Honey Pet Stain & Odor Miracle4.3
Best Cat Urine Spray CleanerBiokleen Bac-Out Stain & Odor Remover Foam Spray4.4

*Ratings are from Amazon at the time of publication and can change

Best Cat Urine Cleaner and Odor Remover Overall: Rocco & Roxie Professional Strength Stain & Odor Eliminator

Rocco & Roxie Professional Strength Stain & Odor Eliminator is a popular choice among pet owners, and was even given The Carpet and Rug Institute seal of approval. Stains and odors don’t stand a chance with this enzymatic formula. For use on multiple types of surfaces, such as tile, concrete, carpets, upholstery, and diaper pails, Rocco & Roxie deliver a stain and odor eliminator spray that battles the tough messes. As tough as it is, it’s safe to use around pets, children, and even as a pretreatment for your laundry.

Enzymes help control the problem at its source. Clean the area as well as possible. Spray the solution directly on top of the problem spot. Let it stand for the directed amount of time while the enzymes target the ammonia, and then blot the area with a clean cloth. Let the spot dry, and then vacuum over the area. The stain and odor should be gone, leaving behind a light, fresh scent. This spray is free from chlorine, color safe, and nonhazardous. It’s also backed by a 100 percent money-back guarantee.

Rocco & Roxie Professional Strength Stain & Odor Eliminator Key Features:

  • Chlorine-free and safe on colors
  • For use on every surface
  • Certified pet and human safe
  • Can be used on laundry stains
  • Targets ammonia residue

Best Cat Urine Carpet Cleaner: Nature’s Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo

Best Cat Urine Carpet Cleaner
Nature's Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo
Designed to be used with a water-based carpet or steam cleaner, this low-foam formula deep cleans your carpet to eliminate old and new stains.

The best cat urine carpet cleaner is Nature’s Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo for those times you need more than just a spot cleaner. Designed especially for steam cleaners or carpet cleaning machines that use a water base, this carpet shampoo cleans up cat urine and other hard-to-remove stains and odors from a variety of organic material. Thanks to an enzyme attacking system, this carpet solution targets the source of the stain, eliminating it from deep within your floors.

Nature’s Miracle carpet shampoo is a low-foam formula that removes old and new stains. The gentle foaming action also works to completely eliminates odors. The professional strength cleaner offers a light, refreshing scent after you have used it on your carpets. It doesn’t just mask the odor, but gets rid of the unwanted stink instead, which helps discourage future behavioral accidents.

Nature’s Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo Key Features:

  • Professional strength formula
  • Enzymatic action targets the source
  • Works on upholstery
  • Can be used for spot cleaning
  • Penetrates through carpet fibers for a deep clean

Best Budget Cat Urine Cleaner and Odor Remover: OUT! Advanced Stain and Odor Remover

Best Budget Cat Urine Cleaner and Odor Remover
OUT! Advanced Stain and Odor Remover
Using an enzymatic formula, this concentrated cleaner fights through tough stains and odors to neutralize them on contact.

We like OUT! Advanced Stain and Odor Remover when budget is a concern, or you have a house full of pets. It’s an effective cleaner, while only costing you a few dollars out of your pocket. Using both the power of bacteria and enzymes, this concentrated formula removes a host of stains from urine, feces, vomit, and blood. This same powerful duo gets rid of odors permanently, instead of just covering them up and leaving you with a weird mix of smells. Unwanted odors are neutralized, and you’re left with a lingering fresh scent.

Safe to use around pets and children, OUT! cleaning spray doesn’t contain any hazardous chemicals or dangerous materials. It works on old and new problem areas, and deters cats from marking the same spot. A multitude of areas and surfaces can benefit, such as upholstery, carpet, tile, grout, fabric, and even mattresses. It’s not recommended for use on leather or wool. Clean the spot to be treated, spray with OUT! until saturated, wait the allotted time, and blot clean with a dry rag.

OUT! Advanced Stain and Odor Remover Key Features:

  • Safe to use with laundry
  • Safe to use around pets and humans
  • No toxic or harsh chemicals
  • For use on multiple surfaces
  • Cleaning power of bacteria and enzymes

Best Cat Pee Enzyme Cleaner: Sunny & Honey Pet Stain & Odor Miracle

Best Cat Pee Enzyme Cleaner
Sunny & Honey Pet Stain & Odor Miracle
Remove stains and odors from a variety of surface types with the special help of enzymes.

Our favorite enzymatic cleaner is Sunny & Honey Pet Stain & Odor Miracle; not just because the company donates 10 percent of its profits to animal rescues and shelters, but also because it effectively lifts stains and eliminates odors. An enzymatic cleaner doesn’t cover up the problem – it gets rid of it entirely, thanks to the enzymes that eat the organic matter. Once the matter is gone, you have a clean surface. The company is so sure you’ll love it, they offer a 60-day return policy.

Sunny & Honey never tests on animals, and the enzymatic cleaner is safe to use around pets and children. The spray is made in the USA, and certified safe by The Carpet and Rug Institute. Sunny & Honey comes in two scents: spring mint or fall spice. The spray also offers an unscented solution. Use this cleaning spray on carpets, hard floors, furniture, tiles, and rugs to keep your home fresh, and to discourage future marking. You can even use Sunny & Honey in your laundry to remove stubborn stains on your clothes.

Sunny & Honey Pet Stain & Odor Miracle Key Features:

  • 100 percent money-back guarantee
  • Certified safe for pets and humans
  • 10 percent of profits are donated to rescues and shelters
  • Made in the USA
  • Helps prevent repetitive marking

Best Cat Urine Spray Cleaner: Biokleen Bac-Out Stain & Odor Remover Foam Spray

Best Cat Urine Spray Cleaner
Biokleen Bac-Out Stain & Odor Remover Foam Spray
Biokleen uses live bacteria, botanicals, enzymes, and plant-based surfactants to effectively eliminate stains and odors.

Our choice for the best cat urine spray cleaner is Biokleen Bac-Out Stain & Odor Remover Foam Spray due to its natural and plant-based ingredient list. With the help of live – and hungry – bacteria, powerful enzymes, and gentle botanicals, this foaming spray effectively and quickly attacks stains and malodorous odors. The end result is a clean home and no lingering bad scents. This professional strength formula is safe for pets, children, and the environment, and contains no added fragrances.

The Biokleen blend destroys the source of the stain without using harsh chemicals or toxic ingredients. The dual force of bacteria and enzymes attack the organic matter, dissolving the stain and eliminating odors. With the help of lime extract, Biokleen tackles the tough odors that can happen when you have a cat. The spray is also chlorine-free, ammonia-free, and has no phosphate or SLS. This cleaning solution gives your home a fresh clean scent, instead of a litter box aroma. Biokleen is powerful enough to work on other organic stains as well, such as blood, feces, spray, or food.

Biokleen Bac-Out Stain & Odor Remover Foam Spray Key Features:

  • No artificial fragrance
  • Non-toxic, safe formula
  • Made in the USA
  • Uses lime peel extract
  • Plant-based ingredients

Who Should Buy a Cat Urine Cleaner and Odor Remover

If you have a cat, foster cats, or plan on getting a cat, then it would be wise to have an effective urine cleaner and odor remover on hand. First, check with your veterinarian to figure out why your cat is peeing somewhere other than his litter box. Look in on your cat’s health to determine what to do about a urine or spray problem. In the meantime, an effective cleaner can help ease the stress of the situation when accidents do happen.

Pets inevitably come with messes, and it’s our job as pet parents to be prepared for cleaning up after these messes. Whether your cat is learning to use the litter box and missing the mark on several occasions, or your male cat is having a territorial spat with another male, using a cleaner made specifically for such instances can help deter the unwanted behavior. These cleaners work by getting rid of the urine and pheromone smell that is left behind after accidents. If the area is clean, your cat is less likely to mark the spot again.

Best Cat Urine Cleaner and Odor Remover Overall
Rocco & Roxie Professional Strength Stain & Odor Eliminator
Eliminate stains and odors with a cleaner that uses enzymatic bacteria to fight the problem at its source.

Important Features to Consider

Cat urine cleaners and odor removers should not only clean a soiled spot, but also target and neutralize bad odors. An effective cleaner removes stains and is safe around everyone in your household. Here’s what to consider when selecting a cat urine cleaner and odor remover:

  • The main active ingredient. What’s the active ingredient in your cleaner? How are the stains destroyed and the bad odors removed? Pay attention to the ingredients so you can make the best choice for you and your family. Ingredients that are used to fight stains and odors include bacteria, enzymes, citrus extract, surfactants, chlorine dioxide, and hydrogen peroxide. They range from gentle cleansers to harsh chemicals.
  • The method of application. Does the urine cleaner come in a ready-to-use spray bottle, concentrated solution, liquid, or foam spray? For the most convenient cleaner, a spray bottle will be your friend. If you’re looking for something that will last longer, then choose a concentrated solution that you mix with water.
  • Does it get the stain out? The whole point of a urine cleaner is to clean the soiled area. What are the claims and what do previous customers say? Does it take one or two applications? Does the stain disappear completely? Does it work on old stains, too? And is it safe for your floors? Always test a small patch of your floor before using it.
  • Are there any lingering unwanted odors? How well does the cleaner get rid of smells? Though you have to rely on reviews and write-ups, you want a cleaner that will eliminate the stinky odor from your cat’s mishap. You shouldn’t be able to smell where your cat urinated after cleaning it up. Likewise, a good cleaner will also prevent your cat from marking in the same spot repeatedly.
  • Safety regarding use around pets and humans. Take another look at the ingredients. Are you able to use this cleaner around your pets or children? Or does everyone have to vacate the premises in order for you to clean the floor? How you clean your home is a matter of personal preference, but you may need to consider how the urine cleaner works and what it entails to clean up after your cat.

Frequently Asked Questions

How do cat urine cleaners and odor removers work?

The most popular type of urine cleaner and odor remover – the enzymatic and bacterial cleaners – work by breaking down the urine or other organic matter at the cellular level. The enzymes and bacteria eat away at the soiled area, leaving nothing left behind but a clean, sanitary surface. Both the stain and the odor disappear.

Harsh chemicals kill bacteria, but don’t necessarily clean the area. Surfactants, like those found in carpet shampoos, are attracted to both water and residue. They work by encouraging water molecules to grab the organic matter, thus breaking up the urine and washing it away.

How do you remove dried cat urine?

Removing dried cat urine requires neutralizing the alkaline salts found in the urine. The longer cat urine sits, the more it crystallizes. The acidity in vinegar will neutralize the alkaline salts in dried cat urine. Mix together one part vinegar and one part water, then soak the area to be cleaned. Add a little bit of baking soda to the mix to help eliminate odors. You may need to do more than one application.

Will bleach get rid of cat urine smell?

Bleach, or hydrogen peroxide, will disinfect the area, but not get rid of the cat urine smell. However, experts advise to stay away from bleach when it comes to cleaning up after your cat. Cat urine turns in to ammonia, which then reacts with the bleach to give off potentially toxic fumes.

Eliminate cat urine smell with vinegar, baking soda, enzymes, or bacteria. These ingredients target the organic matter, eliminating the source of the problem. No problem, no smell.

Do vinegar and baking soda get rid of cat urine smell?

Cat urine is a stubborn smell that is not easily eradicated. Vinegar and baking soda are an acceptable duo for their combined cleaning power. The vinegar breaks down the urine, while the baking soda absorbs the odor. However, this combination may or may not get out more set-in stains.

Other Cat Urine Cleaners and Odor Removers We Reviewed

Best Cat Urine Cleaner and Odor Remover Overall
Rocco & Roxie Professional Strength Stain & Odor Eliminator
Eliminate stains and odors with a cleaner that uses enzymatic bacteria to fight the problem at its source.

We looked at 20 other cat urine cleaners and odor removers. Even though they didn’t make our 5 best cat urine cleaners and odor removers list, they’re the best of the rest, and are still great options for cleaning up after your cat. The information you need to compare each one is included with the listing.

Citrus Cat Urine Cleaners and Odor Removers

Angry Orange Pet Odor Eliminator

Angry Orange Pet Odor Eliminator

Made from orange peel oil, Angry Orange is non-toxic and biodegradable, and has a light citrus scent.

Key Features:

  • Safe to use on all surfaces
  • Concentrated solution that mixes with water
  • Targets ammonia and methane odors

Cost: $23

Angry Orange Ready-to-Use Citrus Pet Odor Eliminator Spray

Angry Orange Ready-to-Use Citrus Pet Odor Eliminator Spray

Fight stains and odors on contact with a safe and strong citrus-scented spray. Ready to use and no mixing required, this spray works on all types of surfaces.

Key Features:

  • Pet and human safe
  • Made from oranges
  • Twice the strength of other leading brands

Cost: $20

Nature’s Miracle Just for Cats Orange Oxy Stain and Odor Remover

Nature's Miracle Just for Cats Orange Oxy Stain and Odor Remover

Deep clean your rugs, hard floors, furniture, and carpets with Nature’s Miracle Oxy formula, eliminating odors and stains.

Key Features:

  • Light orange scent
  • Safe to use on multiple surfaces
  • Pet and human safe

Cost: $12

OUT! Orange Oxy Stain and Odor Remover

OUT! Orange Oxy Stain and Odor Remover

The oxidized citrus cleaning formula neutralizes odors and eliminates stains.

Key Features:

  • Works on household stains
  • Safe for use around pets and humans
  • Removes pheromones to discourage repeated marking

Cost: $5

Concentrated Cat Urine Cleaners and Odor Removers

Life Miracle Enzyme Cleaner & Pet Odor Eliminator

Life Miracle Enzyme Cleaner & Pet Odor Eliminator

Remove tough stains and smelly odors with an enzymatic solution that is effective on a number of organic materials. Furthermore, it’s safe to use on a myriad of surfaces.

Key Features:

  • Concentrated solution that mixes with water
  • Professional strength formula
  • Non-toxic and safe on colors

Cost: $25

REMOVEURINE Severe Urine Neutralizer

REMOVEURINE Severe Urine Neutralizer

REMOVEURINE is an easy-to-use spray that works on organic odors by neutralizing bacteria. It’s safe to use on water-safe surfaces.

Key Features:

  • Light, fresh scent
  • Professional strength formula
  • Money-back guarantee

Cost: $18

Simple Green Outdoor Odor Eliminator for Pets

Simple Green Outdoor Odor Eliminator for Pets

Made specifically for outdoor materials, such as grass, concrete, brick, artificial turf, and gravel, Simple Green is safe to use around pets and humans.

Key Features:

  • Non-toxic formula
  • Hooks up to your outdoor hose
  • Safe for landscaping

Cost: $26

Thornell Cat Odor-Off

Thornell Cat Odor-Off

Get rid of smelly odors from cat urine or spray with a cleaning liquid that’s safe to use on all types of surfaces.

Key Features:

  • Non-toxic and biodegradable
  • Concentrated solution that mixes with water
  • Safe around pets and humans

Cost: $14

Enzymatic Cat Urine Cleaners and Odor Removers Under $15

Nature’s Miracle Advanced Stain and Odor Eliminator

Nature's Miracle Advanced Stain and Odor Eliminator

Able to tackle heavy pet messes, this enzymatic formula handles both stubborn stains and tough odors.

Key Features:

  • For use on multiple surfaces
  • Light, fresh scent
  • Safe to use around pets and humans

Cost: $8

Simple Solution Cat Stain and Odor Remover

Simple Solution Cat Stain and Odor Remover

Safe to use around pets and humans, and designed for most water-safe surfaces, Simple Solution eliminates stains and odors.

Key Features:

  • Manufactured in the USA
  • Professional strength formula
  • Foam, mist, or stream spray

Cost: $8

Simple Solution Hardfloor Pet Stain & Odor Remover

Simple Solution Hardfloor Pet Stain & Odor Remover

Made specifically for hardwood floors, tile, stone, brick, and concrete, this stain and odor remover gets out common pet messes through the natural process of enzymes.

Key Features:

  • Mist, stream, and foam spray
  • Made in the USA
  • Bacteria and enzyme solution

Cost: $8

TriNova Natural Pet Stain and Odor Remover Eliminator

TriNova Natural Pet Stain and Odor Remover Eliminator

Safe to use around pets and humans, but professional strength, TriNova Natural makes a spray that’s both tough on stains and non-toxic.

Key Features:

  • Safe to use on most surfaces
  • 100 percent money-back guarantee
  • Natural and organic ingredients

Cost $14

Urine Gone Stain & Odor Eliminator

Urine Gone Stain & Odor Eliminator

Safe for a multitude of surfaces, this cleaning spray works via an enzyme solution.

Key Features:

  • Easy to use spray
  • Non-toxic formula
  • For use on various surfaces

Cost: $10

urineOFF Cat & Kitten Stain and Odor Remover

urineOFF Cat & Kitten Stain and Odor Remover

Made with pheromone blockers to prevent cats from marking, this enzymatic spray also eliminates stains and odors; it doesn’t just mask them.

Key Features:

  • Veterinarian recommended
  • USDA certified bio-based product
  • Keep out of reach of children and pets

Cost: $12

Enzymatic Cat Urine Cleaners and Odor Removers Over $15

Amaziing Solutions Pet Odor Eliminator and Stain Remover

Amaziing Solutions Pet Odor Eliminator and Stain Remover

Amaziing Solutions enzymatic formula gets rid of stains and odors quickly.

Key Features:

  • Made in the USA
  • 100 percent satisfaction guarantee
  • The Carpet and Rug Institute seal of approval

Cost: $20

BUBBAS Super Strength Commercial Enzyme Cleaner

BUBBAS Super Strength Commercial Enzyme Cleaner

This super strength enzymatic cleaner is good to use in many areas, including the laundry. It destroys the bacteria in cat urine on contact.

Key Features:

  • Works on other organic material, such as food
  • Veterinarian recommended
  • The Carpet and Rug Institute seal of approval

Cost: $20

Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator

Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator

For cleaning multiple types of surfaces, this stain and odor eliminator uses bacteria and enzymes to attack the urine matter and devour it.

Key Features:

  • Made in the USA
  • Chlorine-free and color-safe
  • Simple ingredient list

Cost: $19

Other Cat Urine Cleaners and Odor Removers

Mister Max Unscented Anti Icky Poo Odor Remover

Mister Max Unscented Anti Icky Poo Odor Remover

Recommended by veterinarians, Mister Max stain and odor remover uses live bacteria to eliminate the source of the problem.

Key Features:

  • Keep out of reach of children and pets
  • Works on all surfaces
  • Removes odors by eliminating bacteria

Cost: $30

Nature’s Miracle Urine Destroyer

Nature's Miracle Urine Destroyer

For use on all types of surfaces, Nature’s Miracle disinfectant works via enzymes to treat the toughest stains. It is also safe to use around pets and children.

Key Features:

  • Uses chlorine dioxide to kill bacteria
  • Light, fresh scent
  • Clear view strip on bottle for measuring

Cost: $12

Woolite Advanced Pet Stain & Odor Remover

Woolite Advanced Pet Stain & Odor Remover

Woolite stain and odor remover kills bacteria at the source. It can be used on multiple types of surfaces.

Key Features:

  • Cleans and sanitizes
  • Stream or spray option
  • Pet and human safe

Cost: $5

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